Which of the following is characteristic of GBS CSF analysis?

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Prepare for the Neuromuscular Interventions Test with flashcards and multiple-choice questions. Each question includes hints and explanations. Get ready to ace your exam!

Multiple Choice

Which of the following is characteristic of GBS CSF analysis?

Explanation:
Guillain-Barré syndrome often shows albuminocytologic dissociation in CSF: elevated protein without an accompanying increase in white blood cells. This occurs because demyelination and inflammatory damage at the nerve roots allow more protein to leak into the CSF, while there is little meningeal inflammation to raise the cell count. So the hallmark pattern is high CSF protein with a normal WBC count. Patterns with elevated white blood cells suggest meningitis or other CNS infections, while low protein with high WBC isn’t typical of GBS.

Guillain-Barré syndrome often shows albuminocytologic dissociation in CSF: elevated protein without an accompanying increase in white blood cells. This occurs because demyelination and inflammatory damage at the nerve roots allow more protein to leak into the CSF, while there is little meningeal inflammation to raise the cell count. So the hallmark pattern is high CSF protein with a normal WBC count. Patterns with elevated white blood cells suggest meningitis or other CNS infections, while low protein with high WBC isn’t typical of GBS.

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