Relapsing-Remitting MS is best described as which of the following?

• A. Progressive progression without relapses.
• B. Exacerbations with partial or complete recovery; MRI activity distinguishes active vs not active.
• C. Steady deterioration with no remissions.
• D. Onset in late adulthood with rapid decline.

Answer: (B)

Relapsing-Remitting MS is defined by episodes of new or worsening neurologic symptoms (relapses) that occur relatively abruptly and are followed by partial or complete recovery (remissions). During relapses, inflammatory activity drives new lesion formation, which MRI often shows as gadolinium-enhancing lesions—indicating active disease. Between relapses, symptoms can stabilize and MRI findings may show reduced or no active inflammation, reflecting quiescent periods. This pattern distinguishes RRMS from other MS forms that involve steady, progressive deterioration without distinct relapses. RRMS commonly begins in young adulthood, not late in life, and many patients may later progress to a secondary-progressive course.