In X-linked muscular dystrophy, what is the probability a son of a carrier mother will be affected?

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Prepare for the Neuromuscular Interventions Test with flashcards and multiple-choice questions. Each question includes hints and explanations. Get ready to ace your exam!

Multiple Choice

In X-linked muscular dystrophy, what is the probability a son of a carrier mother will be affected?

Explanation:
X-linked recessive inheritance is at play here. A carrier mother has one normal X and one mutated X. Sons get their X from the mother and a Y from the father. For each pregnancy, there’s a 50% chance the son inherits the mutated X and is affected, and a 50% chance he inherits the normal X and remains unaffected. Since a single mutated X causes disease in males, the likelihood for a son of a carrier mother to be affected is 50%.

X-linked recessive inheritance is at play here. A carrier mother has one normal X and one mutated X. Sons get their X from the mother and a Y from the father. For each pregnancy, there’s a 50% chance the son inherits the mutated X and is affected, and a 50% chance he inherits the normal X and remains unaffected. Since a single mutated X causes disease in males, the likelihood for a son of a carrier mother to be affected is 50%.

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