Gliadel wafers contain which chemotherapeutic agent?

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Multiple Choice

Gliadel wafers contain which chemotherapeutic agent?

Explanation:
Gliadel wafers deliver chemotherapy directly to the brain tissue left after tumor resection, using local release to bypass the blood–brain barrier. The agent in these wafers is carmustine, a nitrosourea alkylating drug that penetrates surrounding tumor tissue and damages DNA to kill cancer cells. This targeted, local delivery reduces systemic exposure compared with intravenous options. Methotrexate, cisplatin, and vincristine are not formulated as Gliadel wafers and are used differently in cancer treatment, whereas carmustine in this wafer form is specifically designed for this brain-local delivery.

Gliadel wafers deliver chemotherapy directly to the brain tissue left after tumor resection, using local release to bypass the blood–brain barrier. The agent in these wafers is carmustine, a nitrosourea alkylating drug that penetrates surrounding tumor tissue and damages DNA to kill cancer cells. This targeted, local delivery reduces systemic exposure compared with intravenous options. Methotrexate, cisplatin, and vincristine are not formulated as Gliadel wafers and are used differently in cancer treatment, whereas carmustine in this wafer form is specifically designed for this brain-local delivery.

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